Zhi-Gang Jiang Selected Research

3-aminopyridine-2-carboxaldehyde thiosemicarbazone (triapine)

1/2018	PAN-811 prevents chemotherapy-induced cognitive impairment and preserves neurogenesis in the hippocampus of adult rats.
1/2016	PAN-811 Blocks Chemotherapy Drug-Induced In Vitro Neurotoxicity, While Not Affecting Suppression of Cancer Cell Growth.
1/2009	PAN-811 inhibits oxidative stress-induced cell death of human Alzheimer's disease-derived and age-matched olfactory neuroepithelial cells via suppression of intracellular reactive oxygen species.
7/2007	PAN-811 provides neuroprotection against glutamate toxicity by suppressing activation of JNK and p38 MAPK.
1/2006	A multifunctional cytoprotective agent that reduces neurodegeneration after ischemia.
1/2006	Neuroprotective activity of 3-aminopyridine-2-carboxaldehyde thiosemicarbazone (PAN-811), a cancer therapeutic agent.

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Zhi-Gang Jiang Research Topics

Disease

8	Neoplasms (Cancer) 01/2019 - 01/2006
3	Neoplasm Metastasis (Metastasis) 01/2019 - 09/2012
3	Neurodegenerative Diseases (Neurodegenerative Disease) 12/2013 - 01/2006
2	Cognitive Dysfunction 01/2018 - 01/2016
2	Chemotherapy-Related Cognitive Impairment 01/2018 - 01/2016
1	Breast Neoplasms (Breast Cancer) 01/2019
1	Melanoma (Melanoma, Malignant) 01/2019
1	Adenocarcinoma 01/2019
1	Cytomegalovirus Infections (Inclusion Disease) 11/2010
1	Infections 11/2010
1	Alzheimer Disease (Alzheimer's Disease) 01/2009
1	Amyloid Plaque 01/2009
1	Hypoglycemia (Reactive Hypoglycemia) 07/2007
1	Hypoxia (Hypoxemia) 07/2007
1	Ischemic Stroke 01/2006
1	Infarction (Infarctions) 01/2006
1	Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome) 01/2006

Drug/Important Bio-Agent (IBA)

6	3-aminopyridine-2-carboxaldehyde thiosemicarbazone (triapine)IBA 01/2018 - 01/2006
5	Pharmaceutical PreparationsIBA 01/2018 - 01/2006
3	Ribonucleotide Reductases (Ribonucleotide Reductase)IBA 01/2018 - 01/2006
3	Neuroprotective AgentsIBA 01/2016 - 01/2006
2	DNA (Deoxyribonucleic Acid)IBA 11/2010 - 01/2006
1	Proteins (Proteins, Gene)FDA Link 01/2019
1	Monoclonal AntibodiesIBA 01/2019
1	Aspartic Acid (Aspartate)FDA Link 01/2019
1	src-Family KinasesIBA 01/2019
1	Mixed Function Oxygenases (Monooxygenases)IBA 01/2019
1	Immunoconjugates (Immunoconjugate)IBA 01/2019
1	GTPase-Activating Proteins (GTPase-Activating Protein)IBA 01/2019
1	Long-Acting Thyroid Stimulator (LATS)IBA 01/2019
1	Fluorouracil (Carac)FDA LinkGeneric 01/2016
1	Transcription Factors (Transcription Factor)IBA 09/2012
1	brincidofovirIBA 11/2010
1	EstersIBA 11/2010
1	LipidsIBA 11/2010
1	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2009
1	Amyloid beta-PeptidesIBA 01/2009
1	Glutamic Acid (Glutamate)FDA Link 07/2007
1	VeratridineIBA 07/2007
1	StaurosporineIBA 07/2007
1	EnzymesIBA 01/2006

Therapy/Procedure

4	Therapeutics 01/2019 - 01/2006
3	Drug Therapy (Chemotherapy) 01/2018 - 12/2013